Perennial celandine is used in folk medicine mainly because it is a yellow milk juice. The plant is located near settlements in Europe, Asia and North America. With the application of synthetic drugs, celandine is increasingly forgotten, so it is often called weeds. Earlier, the plant was prescribed to combat warts and skin diseases. Clinical efficacy has been demonstrated in two controlled studies. From papillomas, celandine is applied to problem areas of the skin in the form of an ointment or gel.
Composition and beneficial properties of celandine for papillomavirus
Celandine contains about 20 isoquinoline alkaloids, mainly in milk juice. The concentration of alkaloids in grass is 0, 48-1, 04%, in roots - up to 1. 95%.
Other chemical compounds in celandine from papillomas:
- organic acids (chelidonic, malic, citric, ferulic acids);
- derivatives of phenolic acids;
- saponins, large amounts of calcium salts and proteolytic enzymes;
- flavonoids;
- biogenic amines (including histamine, tyramine);
- trace amounts of essential oil;
- carotenes;
- vitamin C.
Glycogen is a preservative in celandine. The seeds contain 40-60% vegetable oil. The plant has a bad odor and a bitter taste. Strong odors can cause sneezing, coughing and even vomiting in sensitive people.
Celandine was first found in temperate and warm regions of Europe and Asia, as well as in the Mediterranean, including North Africa. It was brought to North America by immigrants who used it as a remedy for skin diseases. Celandine is a typical weed, ie. grows in ruins, debris, courtyards, fences and hedges, walls, fences, fields and pastures.
Celandine stems are obtained from a thick rhizome with an orange inside (like a milky sap). The flowers consist of two cups, four golden yellow, ovate petals and numerous stamens. A 3-4 cm long capsule is formed from the ovary. Black seeds contain an oil supplement consumed by ants. They are also distributed in the area.
Celandine is used to treat spasms of the biliary tract and gastrointestinal tract. According to traditional medicine, celandine has not been proven to cure warts. Celandine stems, leaves and flowers contain up to 1% alkaloids - chelidonine, coptisine and sanguinarin.
According to research, the plant has mainly anticonvulsant and choleretic effects. Therefore, its use in medically spasmodic disorders of the biliary tract and gastrointestinal tract has been medically proven.
Celandine also has mild analgesic, cell division inhibitory and antiviral effects. The last two effects may explain the long-term use of celandine against warts (caused by viruses).
In medicine, celandine collected during flowering (only the surface parts of the plant) is used. It is recommended to use only ready-made preparations with standardized alkaloids. The reason is that the plant parts themselves contain an indefinite amount of alkaloids. Excessive plant matter damages the liver.
Almost all parts of celandine contain alkaloids. Contains 0. 1% to 1% alkaloids, depending on body origin and drying conditions. Laboratory studies have identified more than 30 different benzylisoquinoline derivatives (such as benzophenatridine, protoberberin, and protopine). Coptizin is the predominant alkaloid, accounting for up to 90%. Chelidon is the main alkaloid in the roots. Other alkaloids in grasses and roots are berberine, chelerithrin, sparteine, helidoxanthin and sanguinarine. In the fall, chemicals accumulate in the roots, which then become highly toxic.
It contains small amounts of various plant acids - helidonic acid, citric acid, malic acid and caffeic acid. Celandine is not rich in flavonoids. The orange-yellow color of milk is due to carotenoids and some alkaloids such as berberine.
Celandine has an antispasmodic effect on the upper digestive tract and stimulates bile flow. Antispasmodic effects are now considered proven. Only a few years ago it was possible to prove its choleretic effect. In addition, antimicrobial, antiviral and antitumor effects have been demonstrated for the extracts.
Methods of application in the treatment of pathology
Celandine is a folk remedy, so it is recommended to measure the benefits and risks before use. A statement was issued advising not to take celandine drugs because of its adverse effects on the liver.
Traditionally, fresh milk juice is used to treat warts, corneas and calluses. Proteolytic and antiviral mechanisms are discussed as the main therapeutic actions. Currently, alkaloid extracts are widely used as standard drugs.
The main use of celandine is in the treatment of skin diseases such as warts or calluses. For cramps in the upper digestive system, the plant was previously used as a tea or tincture.
Internal use of celandine is no longer recommended. Due to the high content of toxic alkaloids in the whole plant, it causes poisoning, especially in the roots. On the contrary, the toxic effects of dried herbs are reduced. It should be noted that the composition of toxic components varies depending on the location, plant and season. Everyone has a different constitution, and therefore their sensitivity to toxins is different. If the plant is used externally, in some cases it can irritate the skin or cause allergies.
Celandine-based pharmaceuticals for papillomas
Ready-made products containing celandine are available in capsules, dragees, tablets and drops. It is recommended to use Papilloma celandine according to the instructions on the appropriate packaging or on the advice of a doctor. Traditionally, herbal milk or celandine tincture is used to get rid of warts. Your doctor will tell you how to use the drug for papillomas.
There have been reports of acute liver damage in patients treated with celandine drugs since the late 20th century. Laboratory tests have confirmed the high sensitivity of human hepatocytes to the alkaloids contained in celandine. As a result, celandine preparations are now available in pharmacies. According to the European Medical Agency in 2010, the benefits of medication do not balance the risks to patients' health.
Folk recipes based on celandine for HPV
Not everyone knows how to properly use celandine. Due to its toxic properties, treatment with a plant can be carried out only under the supervision of a physician. The maximum daily dose is 12-30 mg of alkaloids, ie 2-5 g of dry grass. When treating warts, it is recommended to treat warts with milk several times a day, trying to prevent the formation of blisters on healthy skin. Care should be taken not to make this juice visible, as it creates a strong burning sensation. Bandages with milk juice are useful in the treatment of skin mycoses and wounds that are difficult to heal.
Decoctions, infusions and capsules
Human papillomavirus and stomach cramps with menstrual problems, celandine tea or capsules can help. In this case, an antispasmodic feature manifests itself. However, internal use is not recommended as the ingredient may be toxic. Very high doses and long-term use increase the risk of developing gastrointestinal diseases.
Diluted tea and diluted tincture can be used externally for skin diseases - eczema, warts or acne. It is recommended to pour 200 ml of boiling water on a teaspoon and infuse for 10 minutes. Then soak a piece of tea and apply a compress to the affected area.
Fat solutions and milk
Celandine milk is used for the treatment of warts and corns due to its anti-inflammatory alkaloids. It is recommended to cut a few stems of celandine and apply the leaking yellow juice directly to the affected area 2-3 times a day for several weeks. Due to the irritating effect of the juice should be applied only to the diseased tissue.
You can also prepare a tincture of flowering grass or root and use it as a milky juice. Celandine tincture is available in health food stores. Because the tincture is not as strong as the juice, the duration of use increases.
Side effects and contraindications
Rarely, gastrointestinal complaints occur. In some patients, long-term use of celandine has worsened liver function and developed jaundice. This may be due to an overdose of alkaloids or misuse (for example, severe inflammation of the liver or bile ducts). Overdose of celandine can also cause abdominal pain, intestinal colic and bleeding in the urine.
Isoquinoline alkaloids are responsible for toxic effects. Symptoms of poisoning include pain and burning in the mouth, salivation, diarrhea, and coughing up blood. In severe cases, dizziness, loss of consciousness (including deep coma), decreased blood pressure and tachycardia occur. Cases of fatal intoxication have been reported (in children). Celandine juice can also cause skin irritation (burning, swelling, ulcers) and conjunctivitis (burning, watery eyes). Animal poisoning usually does not occur because they avoid celandine due to its unpleasant odor and taste.
It is necessary to follow the dosage and duration of use indicated inside or taken from the doctor. Continuously, celandine should be used for a maximum of four weeks.
Celandine should not be used in existing or past liver disease, gallstones, inflammation of the bile ducts, bile duct obstruction, or liver damage. In addition, pregnant women, breastfeeding women and children under 12 years of age should avoid the use of celandine.
If symptoms of liver damage (eg, yellowing of the skin or eyes, dark urine, pain in the upper abdomen, nausea, loss of appetite) occur during treatment, treatment should be stopped immediately and a physician should be consulted.
Preparations with celandine can not be used for gastric ulcer, glaucoma and acute catarrh of the gastrointestinal tract. There is a risk of developing glaucoma with long-term use of celandine alkaloids.